The latest science for permanent pain relief
Unlike conventional treatments that only focus on reducing symptoms, Aivo targets the scientifically proven root cause of chronic pain: your brain.
Professor Vania Apkarian
Professor Vania Apkarian of Northwestern University is a world-renowned neuroscientist who first discovered that chronic pain is maintained by emotional brain circuits, not tissue damage. With over two decades of experience working with thousands of people suffering from chronic pain, Professor Apkarian is revered by a global following of leading pain researchers, pain psychologists, physical therapists, and well-informed patient advocates.
Professor Apkarian’s research emphasizes that emotional learning and memory underlie the long-term suffering of chronic pain. His pioneering work highlights that multi-modal therapy, including Mindfulness and Cognitive Behavioral Therapy, can relieve and reverse chronic pain.
Professor Apkarian’s research has been featured in Life Magazine, New York Times, Wall Street Journal, BBC, Scientific American, New Scientist, Nature News, PBS, Men’s Health, US News and World Report, and the National Pain Report.
What is the Aivo Biotype?
The Aivo Biotype is a scientific classification of a person’s pain. Biotypes were originally discovered by Professor Apkarian using neuroimaging to detect patterns of brain connectivity.
Your biotype serves as the basis for your personalized treatment. As your biotype may change during the treatment, we periodically reassess it to ensure the treatment path we offer is always the right one for you in each stage of recovery.
Think of the Aivo Biotype as the key to understanding your individual pain trajectory. Your biotype allows us to unravel the precise steps that will guide you to pain relief.
Aivo rewires your brain for lasting relief
Feel relief in weeks. Stop the pain rollercoaster with sustained relief.
Other treatments offer short-lived results
Standard pain management provides inconsistent relief and the pain always comes back. These treatments don’t provide sustainable relief because they don’t address how your brain has adapted to pain.
Permanent relief requires brain rewiring
Aivo provides continuous care and identifies unique combinations of treatments that work best for you. With daily use of Aivo, your brain can rewire itself into a lasting state of recovery.
Aivo is evidence-based
With nearly $100M in funding for the research and hundreds of peer-reviewed publications, there is a staggering body of evidence supporting the Aivo approach.
Our latest publication is currently being peer reviewed:
"Smartphone-Delivered Pain Self-Management Education For Chronic Low Back Pain: A Usability Study"
If you want to be among the first ones to read it we'll send you the download link to your email.
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Some key peer reviewed publications about the science behind Aivo
- Effect of pain reprocessing therapy vs placebo and usual care for patients with chronic back pain (2021) Yoni K Ashar, Alan Gordon, Howard Schubiner et al. - JAMA Psychiatry September 2021
- Deconstructing biomarkers for chronic pain (2019). Diane Reckziegel, Etienne Vachon-Presseau, Bogdan Petre, Thomas J Schnitzer, Marwan N Baliki, A Vania Apkarian - Pain, May 2019.
- The emotional brain as a predictor and amplifier of chronic pain (2016). E Vachon-Presseau, M V Centeno, W Ren, S E Berger, P Tétreault, M Ghantous, A Baria, M Farmer, M N Baliki, T J Schnitzer, A V Apkarian - Journal of Dental Research, June 2016.
- Nociception, pain, negative moods, and behavior selection (2015). Marwan N Baliki, A Vania Apkarian - Neuron, August 2015.
- Corticostriatal functional connectivity predicts transition to chronic back pain (2012). Marwan N Baliki, Bogdan Petre, Souraya Torbey, Kristina M Herrmann, Lejian Huang, Thomas J Schnitzer, Howard L Fields, A Vania Apkarian - Nature Neuroscience, July 2012.
- Brain morphological signatures for chronic pain (2011). Marwan N Baliki, Thomas J Schnitzer, William R Bauer, A Vania Apkari - PLOS One, October 2011.
- Towards a theory of chronic pain (2009). A Vania Apkarian, Marwan N Baliki, Paul Y Geha - Progress in Neurobiology, February 2009.
- Chronic Pain and the emotional brain (2006). Marwan N Baliki, Dante R Chialvo, Paul Y Geha, Robert M Levy, R Norman Harden, Todd B Parrish, A Vania Apkarian - The Journal of Neuroscience, November 2006.